EGRIFTA is an analog of growth hormone releasing factor and is currently the only FDA-approved therapy for HIV patients. The FDA has approved it to be used as a drug to reduce the excess abdominal fat in HIV infected patients.
EGRIFTA comes in a novel single-vial formation and is four times more potent than the currently available formulation of EGRIFTA in the market. The current formulation requires 2.0 ml of injection, however, the single vial formulation requires only 0.35 ml of injection. In addition, the new formula is stable at room temperature and doesn’t require special storage to distribute it to the patients.
Tesamorelin (INN) (trade name Egrifta) is a synthetic form of growth-hormone-releasing hormone (GHRH) which is used in the treatment of HIV-associated lipodystrophy, approved initially in 2010. It is produced and developed by Theratechnologies, Inc. of Canada. The drug is a synthetic peptide consisting of all 44 amino acids of human GHRH with the addition of a trans-3-hexenoic acid group
Tesamorelin therapy may cause glucose intolerance and increase the risk of type 2-diabetes, so it is contraindicated in pregnancy. It is also contraindicated in pregnancy (category X) because it may cause harm to fetus. It also causes disruption of hypothalamic-pituitary axis due to pituitary gland tumor, head irradiation and hypopituitarism
ChemSpider ID: 34982925
Elimination half-life: 26–38 min
Trade name: Egrifta
ChemSpider ID: 34982925
PubChem CID: 16137828
Formula: C221H366N72O67S
Uses
This medication is used to reduce excess fat in the stomach area (abdomen) in people with HIV infection who have changes in the way their body fat is distributed. Some HIV drugs may cause this side effect (increased fat in the upper back and stomach areas, decreased fat in the arms and legs). Tesamorelin works by causing your body to make more growth hormone. https://jonabiotech.com/
This medication should not be used for weight loss.
How to use Tesamorelin Solution, Reconstituted (Recon Soln)
Read the Patient Information Leaflet and Patient Instructions for Use provided by your pharmacist before starting this medication and each time you get a refill. A health care professional will teach you how to properly use this medication. Learn all preparation and usage instructions in the product package or from your health care professional. If any of the information is unclear, consult your doctor or pharmacist.
Wash your hands with soap and water before using this medication. Before using, check this product visually for particles or discoloration. If either is present, do not use the liquid.
Be the first to review “Tesamorelin (Egrifta)”