Venetoclax tablet 100mg is a BCL-2 inhibitor indicated for the treatment of patients with chronic lymphocytic leukemia (CLL) with 17p deletion, as detected by an FDA approved test, who have received at least one prior therapy.
Venetoclax tablet 100mg is a tablet, taken by mouth.
Venetoclax should be taken orally once daily with a meal and water.
Dosage may be adjusted based on side effects.
Take venetoclax exactly as prescribed.
Swallow venetoclax tablets whole. Do not crush, chew, break or dissolve tablets.
Do not change your dose or stop venetoclax.
Take your dose of Venetoclax tablet 100mg at approximately the same time each day. If you miss a dose of venetoclax by less than 8 hours, take the missed dose right away. Then take your next dose as usual. If you miss a dose of venetoclax and it has been more than 8 hours, wait and take the next dose of venetoclax at your usual time.
Do not take more than 1 dose of venetoclax at one time. Call your health care provider right away if you take too much.
You should not drink grapefruit juice, eat grapefruit, Seville oranges (often used in marmalades), or starfruit while you are taking venetoclax. These foods may increase the amount of venetoclax in your blood. https://jonabiotech.com/
The amount of venetoclax that you will receive depends on many factors, your general health or other health problems, and the type of cancer or condition being treated.
Venetoclax, sold under the brand names Venclexta and Venclyxto, is a medication used to treat adults with chronic lymphocytic leukemia or small lymphocytic lymphoma. The most common side effects are low levels of neutrophils, diarrhea, nausea, anemia, nose and throat infection and tiredness
Other names: GDC-0199, ABT-199, RG-7601
Elimination half-life: ~26 hours
Molar mass: 868.45 g·mol−1
ATC code: L01XX52 (WHO)
License data: EU EMA: by INN; US DailyMed: Venetoclax
Metabolism: Liver (CYP3A4, CYP3A5)